cGMP Plastic Ampoule Blow Fill Seal Machine IV Solution Bottle Bfs Apparatus

• After-sales Service: Field Installation, Commissioning and Training
• Warranty: 1 Year
• Type: Volumetric Filling Machine
• Model NO.: Customized IVEN -1
• Automatic Grade: Automatic
• Material Type: Granular
• Filling Valve Head: Multi-Head
• Feed Cylinder Structure: Multi-Room Feeding
• Dosing Device: Capacity Cup
• Filling Principle: Pressure
• Packaging Container Lifting Structure: Pneumatic Lifting
• Structure: Rotary
• Packaging: Box
• Packaging Material: Plastic
• Deflasher: Internal Punching
• Power Source: 3p/AC380V
• Installed Power: 42kw
• Machine Structure: Dark Side White Side Unseperation
• Packing Materials: PE/PP
• Capacity (Bottle Per Hour): The Capacity Is 3000 PCS/Hour(1ml); The Capacity I
• Filling Accuracy: 1.5% (Based on 5ml) with Purifie
• Manufacturing Standard: cGMP
• Transport Package: Stardard Packing
• Specification: customized
• Trademark: IVEN
• Origin: China

Product Description

Aseptic Pharmaceutical Filling and Sealing Technology/Automatic BFS Machine

 

Product Description

The BFS is a dedicated state of the art system, enabling primary packaging of bulk pharmaceutical solutions into plastic containers of polypropylene or high density polyethylene or low density PE, using a Blow-Fill-Seal (BFS) technology.
The BFS are performed automatically in a single machine under a controlled environment (sterile filtered air-shower).
* extrusion of plastic granulate into a parison at high temperatures
* blow-moulding of parison into a container with sterile-filtered air
* filling of sterile-filtered solution
* hermetic sealing of filled container

This Filling unit assembly is composed of filling nozzles, the manifold with filling valves, the assembly for sterile  air  shower  around  the  nozzles,  the  guide bars  and  the  drive.  In  most  cases  it  is possible to provide special cylinder drive for shifting the nozzles up and down. Such drive is compact and is particularly suitable for clean ambient. The absence of hydraulic cylinders offer safe and clean assembly right above the filling nozzles.

 

Our Advantages

1.The design, MOC, manufacture, assembly and debugging of the BFS machine meet the requirements of the new GMP standards for production.
2. The plastic bottle blow fill seal machine has advanced equipment, unique and reasonable structure, stable and reliable performance and reliable performance.
* Applicable specification: 0.2ml-1000ml plastic bottle(according to user's requirements).
* Production Capacity: 1000-18000BPH(Customized)
*The number of bottles produced each time: 1-30 bottles/mould, can be selected according to production capacity.
* Filling accuracy: ≤ ±1%.
3.The BFS machine is integrated with bottle making, filling and capping, with compact structure and small footprint, which reduces clean workshop area and saves energy consumption of air conditioner, as well as investment and operating costs.
4.The plastic particles are plasticised by a low-speed long-screw extruder driven by a specially designed servo motor, which can effectively reduce the thermal stress of the material and accurately control the size of the bottle preforms.
5. Each cycle of the machine can be automatically compared and controlled with real time feedback.
 

 6.The 304 stainless steel hopper at the extrusion station of the machine is equipped with a level switch and linked to the feeding device; when the material level is lowered, the "low material" alarm information is displayed on the human-machine interface.
7. High production efficiency, stable product performance, simple and reliable operation and beautiful appearance.
8.For large-capacity products, the container thickness is controlled at 100 points by an advanced thickness controller, and the precision servo motor controls the gap between the mould core and the mould cup.
9.The filling system is accurately calculated by time-pressure method with high filling accuracy, which can meet the filling range of 0.2ml-2000ml to ensure production speed.
10.The equipment has black and white sections, the moving parts are isolated in non-clean area (black area).

Product Parameters

Parameters of BFS Machine
NO	Project	Parameter
1	Size(L×W×H)	3500*1400*2800mm
2	Weight	4.5T
3	Deflasher	Internal punching
4	Power Source	3P/AC380V
5	Installed Power	42Kw
6	Power Rating	30Kw
7	Machine Structure	Dark side white side unseperation
8	Packing Materials	PE/PP
9	Specification	1ml-50ml
11	Capacity (Bottle Per Hour)	The capacity is 3000 pcs/hour(1ml); The capacity is 1500 pcs/hour (10ml);
12	Filling Accuracy	Filling accuracy ±1.5% (based on 5ml) with purified water as filling medium;
13	Manufacturing Standard	cGMP
14	Electrical Standard	IEC 60204-1 Safety of machinery Electrical equipment of machinery GB/T 4728 Graphical symbols for electrical sketches
15	Compress Air	no oil,no water @ 8bar,200NL/min
16	Cooling Water	8-12ºC (pure water)@ 4bar ,2m³/h
17	Pure Steam	125ºC @ 2bar ,25kg/h

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